The Anatomy Perfected: How Our UK/US/CA Pharma Funnel Evolved from 9x to 54x ROAS — 1,664 Verified Purchases
From compliance-driven beginnings to exponential returns — this is how a campaign built for discipline evolved into a system of precision, scale, and resilience.
TL;DR
1,664 verified website purchases tracked across UK, US, and CA.
Average Cost per Purchase: €2.69
Average ROAS: 54x+ peak, 37.6x sustained
Reach: 60,885+ users
Impressions: 902,000+
Total Conversion Value: €144,495.60
From 9x to 54x — and Beyond
Read the Preceding 9x Case Study:
The Anatomy of a High-Performing Ad Campaign: How Every Component Works Together to Build a 9+ ROAS Machine
https://casestudies.zeropenny.co/p/the-anatomy-of-a-high-performing
Back in early 2025, we built a compliant funnel that delivered 9x ROAS in one of Meta’s toughest niches — pharma and supplements. That foundation wasn’t luck; it was system design.
By Q4 2025, that same framework had evolved into a consistent 54x ROAS machine, generating over 1,600+ verified purchases across international markets.
Our formula? Keep the same core. Upgrade the system.
The Foundation: Compliance Meets Conversion
Restricted niches live and die by one rule — what stays approved, scales.
We rebuilt the ad architecture to survive Meta’s filters while sustaining growth velocity:
Creative Direction: Lifestyle imagery with high emotional cues, avoiding medical language or direct claims.
Audience Systems: Layered LAL + retargeting combinations across UK, US, and CA delivering scalable reach under €3 per purchase.
Scaling Model: Progressive CBO scaling, controlled pacing, zero disapprovals.
The Anatomy of a 54x System
We didn’t just improve — we evolved the internal organs of performance.
The Brain: Data intelligence driven by Meta’s CBO with AI-enhanced audience refinement.
The Heart: Storytelling-based creatives that built consumer trust over repetition, not hype.
The Nerves: Rapid replacement system for fatigued creatives and adsets — no downtime, no drops.
The Lungs: Continuous oxygen flow from new LALs — ensuring reach expansion without overspend.
Each part functioned in sync. Together, they built a living, learning system.
Performance Snapshot
Primary KPIs
Total Website Purchases: 1,664 verified
Average Cost per Purchase: €2.69
ROAS: 54x peak / 37.6x sustained
Total Conversion Value: €144,495.60
Secondary KPIs
Reach: 60,885 users
Impressions: 902,117
CTR: ~3.2%
Frequency: 2.4
The Outcome
What started as a 9x performer has evolved into a cross-market system generating €144,495.60 in tracked sales — fully compliant, fully scalable, fully alive.
We didn’t chase luck.
We engineered evolution.
No bans. No breakdowns. Just exponential growth.
54x average ROAS peak
1,600+ purchases verified
Zero compliance flags during scaling
System architecture that can replicate cross-niche
How This Was Possible
This wasn’t a one-off. It was an evolution — born from a disciplined system that turned creative compliance into conversion architecture.
From 9x to 54x, the blueprint remained the same:
structure, adaptation, and precision scaling.
Zero Penny builds ad systems designed to thrive where others break.
💬 Want Similar Results?
Whether you’re scaling pharma, supplements, or other restricted verticals, disciplined architecture and data-driven iteration turn compliance into an advantage. What starts as a survival system can evolve into a 54x performer when structure meets creativity.
Zero Penny builds compliant, conversion-first ad systems engineered for resilience, precision, and scale — designed to reduce cost per sale and maximize longevity in even the toughest niches.
📩 Ready to Evolve Your Campaign from Reactive to Engineered Growth?
If your ads keep breaking, burning out, or getting flagged — it’s time to build a system that adapts, learns, and compounds.Let’s build a system that doesn’t just work — it lasts.
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